In Vitro Evaluation of Antioxidant, Antiglycation and Anti-Protein Denaturation Potentials of Indigenous Myanmar Medicinal Plant Extracts

ABSTRACT

The antioxidant, anti-glycation and anti-protein denaturation potential of test extracts were assessed by hemolysis, antioxidant, antiglycation, and anti-protein denaturation assays. The cytotoxic effect of the tested extracts ranged from 6.18 ± 0.15 to 29.33 ± 1.47%. The highest effect was noted in C. carandas, H. cannabinus, T. chebula and H. indicum in antioxidant assay. The phenolic content ranged from 84.73 to 238.23 mg GAE g−1 of extract and the flavonoid was 36.05 to 184.26 mgRE g−1 of extracts. Antiglycation activity exhibited in M. longifolia, T. chebula, H. cannabinus and H. indicum (leaf). C. carandas, H. cannabinus and H. indicum showed significant IC50 value in protein denaturation.

KEYWORDS:

• Flavonoid
• hemolysis
• protease

Acknowledgments

This research work was financially supported by the Department of Research and Innovation, Ministry of Science and Technology, Myanmar.

Disclosure statement

No potential conflict of interest was reported by the author(s).