Abstract
Background. The main purpose of this study is to review the clinical features of negative loop electrosurgical procedure (LEEP)-cones, in order to lower their rate. Methods. Some 162 patients with LEEP-cones were reviewed. Control cytology, satisfactory-unsatisfactory colposcopy, biopsies and endocervical curettage (ECC) were compared to the presence or absence of cone pathology. Statistical analysis, t-tests and Pearson χ2 tests were performed, with a significance level of p<0.05. Results. Negative cones are associated with unsatisfactory colposcopy in 47/60 cases (78.3%) compared to 13/60 (21.8%) for satisfactory colposcopy (p=0.011). Unsatisfactory colposcopy is associated with a negative ECC in 53/74 (71.6%) cases, compared to 21/74 (28.4%) for satisfactory colposcopy (p=0.024). Finally, negative ECC are associated with negative cones in 32/41 (78%) compared to 9/41 (22%) for positive ECC (p=0.002). Conclusions. Low grade cytology, CIN1 biopsies and ECC should be followed for at least 1 year. This results in a lowering of cone negativity from 60/162 (37%) to 32/162 (19.8%).
| Abbreviations | ||
| CIN | = | cervical intraepithelial neoplasia (grades 1, 2, or 3) |
| ECC | = | endocervical curettage |
| HSIL | = | high grade squamous intraepithelial lesion |
| LEEP | = | loop electrosurgical procedure |
| LSIL | = | low grade squamous intraepithelial lesion |
| Abbreviations | ||
| CIN | = | cervical intraepithelial neoplasia (grades 1, 2, or 3) |
| ECC | = | endocervical curettage |
| HSIL | = | high grade squamous intraepithelial lesion |
| LEEP | = | loop electrosurgical procedure |
| LSIL | = | low grade squamous intraepithelial lesion |