Clinical features of patients with high and normal CSFP in venous pulsating tinnitus

Abstract

Background: Few doctors associate high cerebrospinal fluid pressure (CSFP) with vascular tinnitus. On the basis of predecessors, we found there were some differences in clinical data between patients with elevated versus normal CSFP.

Aims/objectives: To explore the differences in clinical data between the elevated CSFP group and the normal CSFP group.

Materials and methods: A total of 27 patients with venous pulsating tinnitus who underwent measurement of CSFP through IP were reviewed. Clinical data were compared between the two groups.

Result: Twelve patients (44.44%) had high CSFP ranging from 210–245 mm H₂O. Fifteen cases (55.56%) had normal CSFP ranging from 120–190 mm H₂O. Tinnitus disappeared for several hours after IP in 9 patients in thehigh CSFP group but none of the patients in the normal CSFP group, and this difference was significant (p < .001). The mean tinnitus handicap inventory (THI) and visual analog scale (VAS) were 90.33 ± 3.06 and 8.25 ± 0.83, respectively, in the high CSFP group and 83.73 ± 2.81 and 7.73 ± 0.93, respectively, in the normal CSFP group. These differences were statistically significant (p < .001).

Conclusion and significance: Patients in the high CSFP group had more severe tinnitus scores. Tinnitus temporarily disappeared after IP in some patients with high CSFP.

Chinese abstract

背景：很少有医生将高脑脊液压（CSFP）与血管性耳鸣联系起来。在前人研究的基础上, 我们发现CSFP升高患者与CSFP正常患者的临床资料之间存在一定差异。

目的：探讨CSFP升高组与CSFP正常组临床资料之间的差异。

材料与方法：回顾性分析27例静脉搏动性耳鸣患者的临床资料。他们的CSFP通过IP得以检测。比较两组的临床资料。

结果：12例患者（44.44%）有高脑脊液压, 在210-245mmH2O之间, 15例（55.56%）的CSFP在120-190mmH2O之间, 高CSFP组有9例（55.56%）在IP后耳鸣消失数小时, 而正常CSFP组无耳鸣发生, 其差异有显著性（p <0.001）。平均耳鸣障碍量表（THI）和视觉模拟量表（VAS）在高CSFP组分别为90.33±3.06和8.25±0.83, 在正常CSFP组分别为83.73±2.81和7.73±0.93。这些差异具有统计学意义（p<0.001）。

结论及意义：高CSFP组患者耳鸣评分比较严重。部分高CSFP患者IP后耳鸣暂时消失。

Keywords:

• Venous pulsating tinnitus
• lumbar puncture
• cerebrospinal fluid pressure

Disclosure statement

The authors have no other funding, financial relationships, or conflicts of interest to disclose.

Additional information

Funding

This study was supported by National Natural Science Foundation of China (No. 81670933).