Comparison of Retinal Degeneration in the Normal Goldfish and the Megalophthalmic Black Moor Goldfish after Optic Nerve Transection and Lens Extraction

Xi Ying Department of Ophthalmology, Southwest Hospital, Third Military Medical University, Chongqing, China

Maria S.M. Wai Department of Anatomy, Chinese University of Hong Kong, Shatin, N.T. Hong Kong, China

Yi Wang Department of Ophthalmology, Southwest Hospital, Third Military Medical University, Chongqing, China

Jeanie P.C. Lau Department of Anatomy, Chinese University of Hong Kong, Shatin, N.T. Hong Kong, China

Elizabeth Lucy Forster Department of Anatomy, Chinese University of Hong Kong, Shatin, N.T. Hong Kong, China

David T. Yew Department of Anatomy, Chinese University of Hong Kong, Shatin, N.T. Hong Kong, China

Abstract

A comparison in retinal degeneration was studied in the normal goldfish and the megalophthalmic goldfish after optic nerve transection or lens extraction by the TUNEL (Terminal transferase-mediated dUTP nick end labeling) technique. A significant number of TUNEL positive cells appeared in both cases 7 days after injury, with a more prominent result in the megalophthalmic eye. Lens extraction, had less apoptotic cell death in the experimental retinas.

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Comparison of Retinal Degeneration in the Normal Goldfish and the Megalophthalmic Black Moor Goldfish after Optic Nerve Transection and Lens Extraction

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Comparison of Retinal Degeneration in the Normal Goldfish and the Megalophthalmic Black Moor Goldfish after Optic Nerve Transection and Lens Extraction

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