The Nature of the Anticoagulant Effect of Heparin, Protamine, Polybrene and Toluidine Blue: Scandinavian Journal of Clinical and Laboratory Investigation: Vol 14, No 3

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Abstract

Heparin, protamine, polybrene and toluidine blue possess an inhibitory effect on the thromboplastin activation, the action of tissue thromboplastin as well as plasma thromboplastin, and an antithrombin effect.

The anticoagulant effect of all the agents could be neutralized by normal serum as well as serum which had been depleted for Christmas factor by adsorption with BaSO₄.

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The Nature of the Anticoagulant Effect of Heparin, Protamine, Polybrene and Toluidine Blue

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The Nature of the Anticoagulant Effect of Heparin, Protamine, Polybrene and Toluidine Blue

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