Developments in techniques for radioiodination of peptide hormones and other proteins

Abstract

This article presents details on two currently used methods of labelling peptides with radioiodine. The solid phase enzymatic iodination with lactoperoxidase is very suitable for radioimmunoassays and receptor assays. The iodogen labelling technique has been successfully used in this laboratory for preparing radioiodinated radiopharmaceuticals. Other iodination methods are also briefly discussed.

Key Words:

• radioiodination
• solid phase iodination
• enzymatic iodination
• iodogen iodination
• lactoperoxidase in iodination