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Scandinavian Journal of Clinical and Laboratory Investigation Volume 58, 1998 - Issue 8
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Research Article

Relaxing effects of cyclic GMP and cyclic AMP-enhancing agents on the long-lasting contraction to endothelin-1 in the porcine coronary artery

I K Lillestøl Departments of Surgery and
,
K B Helle Physiology, University of Bergen, Bergen, Norwa
&
S Aardal Departments of Surgery and
Pages 625-634 | Published online: 08 Jul 2009
 
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Abstract

In the coronary circulation, endothelin-1 (ET-1) evokes spasms which are difficult to treat when the endothelial integrity is compromised. This study compares several classes of relaxing agents on already established contractions to ET-1 in an in vitro

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