Gastric Emptying of Realistic Meals With and Without Gluten in Patients with Coeliac Disease. Effect of Jejunal Mucosal Recovery

Abstract

Background: Few data are available on disturbed gastric emptying in patients with coeliac disease. The aims of the study were to investigate (a) the presence of delayed gastric emptying; (b) the acute effect on gastric emptying of gliadin; and (c) the effect of jejunal recovery on gastric emptying of meals with or without gluten in such patients. Methods: We measured gastric emptying of two meals in 16 patients with coeliac disease; one meal contained gliadin. Results were compared with those obtained in 24 controls. In 12 patients, both measurements were repeated after mucosal recovery. Statistical analysis was performed using the analysis of variance for repeated measurements and Student's t

• Coeliac Disease Dyspepsia Gastric Emptying Gastric Motility Gluten Malabsorption Steatorrhoea Ultrasound