Fatal Nucleoside-associated Lactic Acidosis in an Obese Woman with Human Immunodeficiency Virus Type 1 Infection on a Very Low-calorie Diet

Abstract

This study reports the case of an obese woman with human immunodeficiency virus type 1 (HIV-1) infection who developed fatal nucleoside-associated lactic acidosis 10 d after she started a weight-loss dietary regimen containing 600 kcal/d. This case suggests that very low-calorie diets may be life threatening for HIV-infected patients receiving nucleoside analogues.