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Scandinavian Journal of Infectious Diseases Volume 35, 2003 - Issue 11-12
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Original Paper

Progressive Multifocal Leukoencephalopathy in a Patient with X-linked Agammaglobulinemia

Takahide Teramoto Department of Pathology, Gifu University School of Medicine, 40 Tsukasa-machi, 500-8705, GifuCorrespondencee-mail. [email protected]
,
Hideo Kaneko Laboratory of Molecular and Cellular Pathology, Hokkaido University School of Medicine
,
Michinori Funato Department of Pathology, Gifu University School of Medicine, 40 Tsukasa-machi, 500-8705, Gifu
,
Hirofumi Sawa Laboratory of Molecular and Cellular Pathology, Hokkaido University School of Medicine
,
Kazuo Nagashima Department of Pathology, Gifu University School of Medicine, 40 Tsukasa-machi, 500-8705, Gifu
,
Yoshinobu Hirose Laboratory of Molecular and Cellular Pathology, Hokkaido University School of Medicine
&
Naomi Kondo Department of Pathology, Gifu University School of Medicine, 40 Tsukasa-machi, 500-8705, Gifu
 show all
Pages 910-911 | Received 24 Jun 2003, Accepted 27 Jul 2003, Published online: 08 Jul 2009
 
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Abstract

To our knowledge, this is the first case report describing progressive multifocal leukoencephalopathy (PML) associated with X-linked agammaglobulinemia. The JC virus was confirmed at autopsy and PML was diagnosed. Humoral immunodeficiency with normal cellular immunity could be infected with JCV.

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