Complete Histological Regression of Kaposi's Sarcoma Following Treatment with Protease Inhibitors Despite Persistence of HHV-8 in Lesions

Abstract

There is no current curative treatment for HIV-related Kaposi's sarcoma. The identification of human herpesvirus-8 as a possible aetiological agent suggests potential efficacy of anti-viral agents. We report here on the complete histological remission of Kaposi's sarcoma following treatment with protease inhibitors, even in patients with limited virological response and persistence of HHV-8.