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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 30, 2000 - Issue 13
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Original Articles

A Novel Route to the Synthesis of 3-Pyridine Carboxaldehydes by Vilsmeier Reagent

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Pages 2269-2274 | Accepted 30 Sep 1999, Published online: 04 Dec 2007
 

Abstract

2-Chloro-5-aryl-3-pyridine carboxaldehydes are obtained by Vilsmeier reaction of 4-aryl-3-buten-2-one oxime. The suspected intermediate N-(2-arylethenyl)acetamides also give the same 2-chloro-5-aryl-3-pyridine carboxaldehydes under identical reaction condition.

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