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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 30, 2000 - Issue 13
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Original Articles

A Synthetic Study of Neutral and Cationic Cholesteryl Derivatives as Gene Vectors

Man-Zhou Zhu Department of Chemistry, University of Science and Technology of China, Hefei, 230026, People's Republic of China
,
Jian-Ning Wei Department of Chemistry, University of Science and Technology of China, Hefei, 230026, People's Republic of China
,
Qi-Hua Wu Department of Chemistry, University of Science and Technology of China, Hefei, 230026, People's Republic of China
,
Xiao-Qi Zheng Department of Chemistry, University of Science and Technology of China, Hefei, 230026, People's Republic of China
&
Qing-Xiang Guo Department of Chemistry, University of Science and Technology of China, Hefei, 230026, People's Republic of China
Pages 2325-2333 | Received 08 Jul 1999, Published online: 04 Dec 2007
 
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Abstract

Some novel neutral and cationic lipids bearing cholesteryl groups were synthesized. These lipids contain ketal units as linker bonds which should be easily biodegradable in cells.

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