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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 30, 2000 - Issue 18
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Original Articles

Regioselective N-Alkylation of 4-Formylimidazole

Qiaogong Su Synthetic Chemistry Department, SmithKline Beecham Pharmaceuticals, 709 Swedeland Road, King of Prussia, PA, 19401
&
Jeffery L. Wood Synthetic Chemistry Department, SmithKline Beecham Pharmaceuticals, 709 Swedeland Road, King of Prussia, PA, 19401
Pages 3383-3389 | Received 08 Dec 1999, Published online: 04 Dec 2007
 
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Abstract

We describe here a high yield and highly regioselective N-alkylation of 4-formylimidazole via reversible Michael Reaction.

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