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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 30, 2000 - Issue 18
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Original Articles

The Preparation of 4,5-Dihydro-3-Aryl-Naphth-[1,2-c]- Isoxazoles From Dilithiated 1-Tetralone Oxime and Aromatic Esters

Charles F. Beam Department of Chemistry and Biochemistry, College of Charleston Charleston, South Carolina, 29424
,
Deborah A. Schady Department of Chemistry and Biochemistry, College of Charleston Charleston, South Carolina, 29424
,
Kelly L. Rose Department of Chemistry and Biochemistry, College of Charleston Charleston, South Carolina, 29424
,
Wayne Kelley Jr. Department of Chemistry and Biochemistry, College of Charleston Charleston, South Carolina, 29424
,
Ronjay Rakkhit Department of Chemistry and Biochemistry, College of Charleston Charleston, South Carolina, 29424
,
Christopher D. Hornsby Department of Chemistry and Biochemistry, College of Charleston Charleston, South Carolina, 29424
&
Shannon L. Studer-Martinez Department of Chemistry and Biochemistry, College of Charleston Charleston, South Carolina, 29424
 show all
Pages 3391-3404 | Received 11 Dec 1999, Published online: 04 Dec 2007
 
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Abstract

Dilithiated 1-tetralone oxime was prepared in excess lithium diisopropylamide and condensed with a variety of esters followed by acid cyclization of C-acylated intermediates to substituted 4,5-dihydronaphth-[1,2-c]-isoxazoles.

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