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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 30, 2000 - Issue 22
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Original Articles

Use of 3,5-Disubstituted 1,2,4-Triazoles for the Synthesis of Peptidomimetics

Jožko Cesar University of Ljubljana, Faculty of Pharmacy, Aškereva 7, 1000, Ljubljana, Slovenia
&
Marija Sollner University of Ljubljana, Faculty of Pharmacy, Aškereva 7, 1000, Ljubljana, Slovenia
Pages 4147-4158 | Received 29 Sep 1999, Published online: 04 Dec 2007
 
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Abstract

The synthesis of 3-acylaminoalkyl-5-alkyloxycarbonyl-1,2,4-triazoles, designed as RGD peptidomimetics, is described and the reactivity of 1,2,4-triazoles under conditions of peptide chemistry is discussed.

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