Synthesis of the FR900482 Tetracyclic Ring System by Oxidation of A 2,3-Dihydro-1H-Pyrrolo[1, 2-a]Indole Derivative

Weihong Zhang Department of Chemistry, Rutgers University, Piscataway, NJ, 08854

Cheng Wang Department of Chemistry, Rutgers University, Piscataway, NJ, 08854

Leslie S. Jimenez Department of Chemistry, Rutgers University, Piscataway, NJ, 08854

Abstract

The tetracyclic FR900482 ring skeleton has been synthesized from the 2,3-dihydro-1H-pyrrolo[1,2-a]indole derivative 5. Treatment of 5 with osmium tetraoxide, hydrogen sulfide, magnesium monoperoxyphthalic acid (MMPP), and triphenylphosphine resulted in the formation of 12.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Synthesis of the FR900482 Tetracyclic Ring System by Oxidation of A 2,3-Dihydro-1H-Pyrrolo[1, 2-a]Indole Derivative

Information for

Open access

Opportunities

Help and information

Synthesis of the FR900482 Tetracyclic Ring System by Oxidation of A 2,3-Dihydro-1H-Pyrrolo[1, 2-a]Indole Derivative

Abstract

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature