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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 30, 2000 - Issue 14
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Original Articles

An Efficient Synthesis of N-Alkyl-1,4-Dihydro-4-Oxo-3-Quinolinecarboxylic Acid via 2-(2',2',2'-Tri-Chloro)Ethylidene-3-Oxo-3-(2''-Chlorophenyl)Propionate

I. A. Sayyed Division of Organic Chemistry (Synthesis), National Chemical Laboratory, Pune, 411008, India
,
D. G. Panse Division of Organic Chemistry (Synthesis), National Chemical Laboratory, Pune, 411008, India
,
B. M. Bhawal Division of Organic Chemistry (Synthesis), National Chemical Laboratory, Pune, 411008, India
&
A. R. A. S. Deshmukh Division of Organic Chemistry (Synthesis), National Chemical Laboratory, Pune, 411008, India
Pages 2533-2540 | Received 19 Jul 1999, Published online: 04 Dec 2007
 
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Abstract

A clay catalyzed synthesis of 2-(2',2',2'-trichloro)ethylidene-3-oxo-3-(2''-chlorophenyl)propionate (2) and its application for the preparation of various N-alkyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids (5a-e) has been described.

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