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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 37, 2007 - Issue 2
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Original Articles

Versatile Spirocyclic Glycine‐Based Nitrones and Their Highly Stereoselective 1,3‐Dipolar Cycloaddition

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Pages 297-308 | Received 16 Mar 2006, Published online: 25 Jul 2007
 

Abstract

A convenient and efficient method for the synthesis of novel spirocyclic nitrones prepared from glycine derivatives is reported. The 1,3‐cycloaddition reactions of the nitrones with alkenes lead to novel isoxazolidines in high yields and with excellent regio‐ and stereoselectivity.

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