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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 37, 2007 - Issue 6
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Original Articles

Convenient Synthesis of 1‐Arylmethyl‐2‐naphtholsFootnote

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Pages 877-888 | Received 28 Aug 2006, Published online: 24 Feb 2007
 

Abstract

A new environmentally benign, two‐step procedure for the synthesis of 1‐arylmethyl‐2‐naphthols in good to excellent yield is reported. It involves microwave‐assisted facile formation of Mannich bases of 2‐naphthol under solvent‐free conditions and subsequent Pd‐catalyzed deamination, leading to formation of title compounds.

Acknowledgments

We are thankful to Natural Sciences and Engineering Research Council (NSERC), the Human Resources and Skills Development Canada's Summer Career Placement Program, and Research Corporation (USA) for financial support.

Notes

This paper was presented at International Congress of Chemistry and Environment 2005, Indore, India.

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