Total Synthesis of Neuroprotective Dictyoquinazol A, B, and C

Abstract

A new protective compound, dictyoquinazol A, was synthesized starting from 5‐methoxy‐2‐nitrobenzoic acid in six‐steps in 36% overall yield. Two derivatives B and C, isolated from the mushroom Dictyophora indusiata, were also synthesized from Dictyoquinazole A.

Keywords:

• dictyoquinazol
• natural products
• neuroprotection
• synthesis

Acknowledgments

This work was supported by the research fund of Korea Health Industry Development Institute (KHIDI) (A010126), Korea.