Strategies towards the Synthesis of 6‐N,N‐Diethylcarbamyloxy‐1,4‐dimethoxy‐ 7‐naphthylboronic Acid

Abstract

After acetylation, condensation between Danishefsky's diene and benzoquinone afforded a stable methoxytriacetoxydihydronaphthalene intermediate, which was subsequently transformed by the Snieckus DOM protocol into the regiospecific 7‐naphthylboronic acid.

Keywords:

• boronic acids
• carbamate esters
• Danishefsky's diene
• Snieckus DOM

Acknowledgments

The authors acknowledge financial support provided by the National Research Foundation and the Universities of the Western Cape and Paderborn.