Graphical Abstracts

Abstract

Graphical Abstract Section

Abstract

Synth. Commun. 2007, 37, 3029

GENERAL SYNTHESIS OF 1‐SUBSTITUTED 2‐METHYLBENZIMIDAZOLES FROM KETONES AND 2‐AMINOACETANILIDE

Svetlana A. Burova, Roman Davis, Russ N. Fitzgerald, Byron S. Johnson, and Richard T. Matsuoka

Chemical Development, GlaxoSmithKline, Research Triangle Park, North Carolina

Abstract

Synth. Commun. 2007, 37, 3041

STRATEGIES TOWARDS THE SYNTHESIS OF 6‐N,N‐DIETHYLCARBAMYLOXY‐1,4‐DIMETHOXY‐7‐NAPHTHYLBORONIC ACID

F. Ameer,¹ I. R. Green,¹ K. Krohn², and M. Sitoza¹

¹Department of Chemistry, University of the Western Cape, Bellville, South Africa

²Department of Chemistry, University of Paderborn, Paderborn, Germany

Acetylated adduct 14 was transformed into boronic acid 27 via DOM.

Abstract

Synth. Commun. 2007, 37, 3059

SYNTHESIS OF NEW TETRAZOLE DERIVATIVES OF α,α‐TREHALOSE

Leandro J. dos Santos,¹ Mara R. C. Couri,¹ Inácio Luduvico,¹ Rosemeire B. Alves,¹ Maria A. F. Prado,² and Rossimiriam P. Freitas Gil¹

¹Departamento de Química—Instituto de Ciências Exatas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil

²Departamento de Química Farmacêutica—Faculdade de Farmácia, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil

Abstract

Synth. Commun. 2007, 37, 3067

OXIDATIVE CONVERSION OF 3‐ALKOXYFURANS TO 2‐HYDROXY‐3(2H)‐FURANONES AND 2‐HYDROXY‐2‐BUTENE‐1‐4‐DIONES WITH 2,3‐DICHLORO‐5,6‐DICYANO‐1,4‐BENZOQUINONE (DDQ) OR PHENYLTRIMETHYLAMMONIUM TRIBROMIDE (PTAB) IN T ‐BUOH

Shinsei Sayama

Department of Chemistry, Fukushima Medical University, Hikariga‐oka, Fukushima, Japan

Abstract

Synth. Commun. 2007, 37, 3077

FACILE AND EFFICIENT SYNTHESIS OF SUBSTITUTED 1,4‐DITHIAFULVALENES FROM β‐DICARBONYL COMPOUNDS

Jiqing Zhang, Yulong Zhao, Dazhi Li, Fushun Liang, and Qun Liu

Department of Chemistry, Northeast Normal University, Changchun, China

A facile and efficient synthetic route to acetyl substituted 1,4‐dithiafulvalenes 3 and alkenoyl substituted 1,4‐dithiofulvalenes 4 under mild conditions has been developed.

Abstract

Synth. Commun. 2007, 37, 3089

MILD AND EFFICIENT DEOXYGENATION OF SULFOXIDES WITH MOCL5/INDIUM SYSTEM

Byung Woo Yoo, Min Suk Song, and Min Chol Park

Department of Advanced Materials Chemistry, Korea University, Jochiwon, Chungnam, South Korea

Abstract

Synth. Commun. 2007, 37, 3095

CHLOROTRIMETHYLSILANE: A POWERFUL LEWIS ACIDIC CATALYST IN MICHAEL‐TYPE FRIEDEL–CRAFTS REACTIONS OF INDOLES AND ENONES

Li‐Wen Xu,^1,2 Wei Zhou,¹ Lei Yang,¹ and Chun‐Gu Xia¹

¹State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences and Graduate School of the Chinese Academy of Sciences, Lanzhou, China

²Key Laboratory of Organosilicon Chemistry and Material Technology of Ministry of Education, Hangzhou Normal University, Hangzhou, China

Abstract

Synth. Commun. 2007, 37, 3105

REGIOSPECIFIC ACETYLATION OF SUBSTITUTED α,α′‐BENZYLIDENEDIMETHANOLS WITH VINYL ACETATE USING PORCINE PANCREAS LIPASE

Tsuyoshi Miura, Yuya Kawashima, Mauko Takahashi, Yasuoki Murakami, and Nobuyuki Imai

Faculty of Pharmacy, Chiba Institute of Science, Chiba, Japan

Abstract

Synth. Commun. 2007, 37, 3111

IONIC‐LIQUID‐INFLUENCED EXPEDITIOUS AND STEREOSELECTIVE SYNTHESIS OF OLEFINS

Sachin V. Bhilare, Nitin B. Darvatkar, Amol R. Deorukhkar, Meghana S. Rasalkar, and Manikrao M. Salunkhe

Department of Chemistry, Institute of Science, Mumbai, India

Abstract

Synth. Commun. 2007, 37, 3119

EFFICIENT AND SIMPLE SYNTHESIS OF SUBSTITUTED 3‐PHENYL‐7‐METHOXYBENZOPYRANS AS PSEUDO‐VITAMIN‐D₃ ANALOGS

Atul Gupta and Suprabhat Ray

Medicinal and Process Chemistry Division, Central Drug Research Institute, Lucknow, India

An efficient and simple synthesis of substituted 3‐phenyl, 7‐methoxybenzopyrans as pseudo vitamin‐D₃ analogues in good yields, under mild rection conditions is described

Abstract

Synth. Commun. 2007, 37, 3127

SYNTHESIS OF 2‐OXAZOLINES AND 2‐THIAZOLINES USING LANTHANIDE AMINO ALKOXIDE

V. Padmavathi, B. Chandra Obula Reddy, P. Thriveni, and A. V. Nagendra Mohan

Department of Chemistry, Sri Venkateswara University, Tirupati, India

New 2‐oxazolines and 2‐thiazolines are prepared from phenacysulfonylacetic acid methyl ester using lanthanide amino alkoxide.

Abstract

Synth. Commun. 2007, 37, 3143

CONVENIENT FORMAL SYNTHESIS OF (±)‐PAROXETINE

Subhash P. Chavan, Dushant A. Khobragade, Ashok B. Pathak, and Uttam R. Kalkote

Division of Organic Chemistry: Technology, National Chemical Laboratory, Pune, India

A formal total synthesis of antidepressant (±)‐paroxetine employing a solvent‐free Heck reaction is disclosed.

Abstract

Synth. Commun. 2007, 37, 3151

FACILE SYNTHESIS OF E‐DIIODOALKENES: H₂O₂‐ACTIVATED REACTION OF ALKYNES WITH IODINE

Alexander O. Terent'ev, Dmitry A. Borisov, Igor B. Krylov, and Gennady I. Nikishin

N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow, Russia

Abstract

Synth. Commun. 2007, 37, 3165

GREEN PROCEDURE FOR THE SYNTHESIS OF PHTHALAZINO[2,3‐ B ]PHTHALAZINE‐5,7,12,14‐TETRAONES

Davood Habibi,¹ Nosratollah Mahmoudi,² and Omid Marvi¹

¹Faculty of Chemistry, Bu‐Ali Sina University, Hamedan, Iran

²Faculty of Sciences, Department of Chemistry, University of Guilan, Iran

Abstract

Synth. Commun. 2007, 37, 3173

ONE‐POT SYNTHESIS OF IMINOIMIDAZOLINES UNDER MICROWAVE IRRADIATION IN SOLVENT‐FREE CONDITIONS

Süleyman Servi and Murat Genc

Department of Chemistry, Firat University, Elazig, Turkey

Substituted iminoimidazolines were synthesized from a one‐pot reaction of aromatic or hetero‐aromatic amines with imidazolidine‐2‐thione under solvent‐free conditions using microwave irradiation with good to excellent yields.

Abstract

Synth. Commun. 2007, 37, 3181

REACTION BETWEEN ORTHO‐HYDROXY AROMATIC ALDEHYDES AND DIALKYL ACETYLENEDICARBOXYLATES IN THE PRESENCE OF SILICA GEL IN SOLVENT‐FREE CONDITIONS

Nader Noshiranzadeh and Ali Ramazani

Department of Chemistry, University of Zanjan, Zanjan, Iran

A two‐component condensation reaction between an ortho‐hydroxy aromatic aldehyde and an electron‐poor acetylenic ester efficiently provides fully substituted electron‐poor aryl vinyl ethers and chromenes in a one‐pot reaction in the presence of silica‐gel in solvent‐free conditions.

Abstract

Synth. Commun. 2007, 37, 3191

MICROWAVE‐PROMOTED EFFICIENT SYNTHESIS OF 2‐PHOSPHABICYCLO[2.2.2]OCTADIENE‐AND OCTENE‐2‐OXIDES UNDER SOLVENT‐FREE CONDITIONS IN DIELS–ALDER REACTION

György Keglevich and Eszter Dudás

Department of Organic Chemistry and Technology, Budapest University of Technology and Economics, Budapest, Hungary

The title compounds were prepared from 1,2‐dihydrophosphinine oxides and dimethyl acetylenedicarboxylate or N‐phenylmaleimide under green chemical conditions.

Abstract

Synth. Commun. 2007, 37, 3201

ALKATRIENYL SULFOXIDES AND SULFONES, VIII: DIELS–ALDER REACTION OF 3‐METHYLPENTA‐1,2,4‐TRIENYL PHENYL SULFOXIDE WITH MALEIC ANHYDRIDE

Valerij C. Christov and Ivaylo K. Ivanov

Department of Chemistry, University of Shumen, Shumen, Bulgaria

Abstract

Synth. Commun. 2007, 37, 3211

A NEW ROUTE FOR THE SYNTHESIS OF SUBSTITUTED PYRIDAZINES

Mohamed Abdel‐Megid

Faculty of Education, Department of Chemistry, Ain‐Shams University, Cairo, Roxy, Egypt

Abstract

Synth. Commun. 2007, 37, 3219

SIMPLE PREPARATION OF SYMMETRICAL CARBOXYLIC ACID ANHYDRIDES BY MEANS OF NA ₂CO₃SOCL₂

F. Kazemi,¹ A. R. Kiasat,² and B. Mombaini²

¹Institute for Advanced Studies in Basic Sciences (IASBS), Zanjan, Iran

²Chemistry Department, College of Science, Shahid Chamran University, Ahvaz, Iran

A convenient and general method for the synthesis of symmetrical carboxylic acid anhydrides using sodium carbonate/thionyl chloride is described.

Abstract

Synth. Commun. 2007, 37, 3225

SYNTHESIS OF FUNCTIONALIZED PYRANO[3,2‐C]PYRIDINES AND THEIR TRANSFORMATIONS TO 4‐HYDROXY‐3[(1E)‐N‐HYDROXYALKANIMIDOYL]PYRIDONES

Farag A. El‐Essawy, Ahmed F. Khattab, Magdy A. Zahran, and Sherif H. Gomaa

Faculty of Science, Chemistry Department, Monoufiya University, Shebin El‐Koam, Egypt

Abstract

Synth. Commun. 2007, 37, 3239

STEREO‐ AND REGIOSELECTIVE THIOLYSIS OF 1,2‐EPOXIDES IN WATER

Barahman Movassagh^1,2 and Mohammad Soleiman‐Beigi¹

¹Department of Chemistry, K. N. Toosi University of Technology, Tehran, Iran

²Kermanshah Oil Refining Company, Kermanshah, Iran

A simple, efficient, stereoselective, and highly regioselective procedure for the synthesis of β‐hydroxy sulfides by thiolysis of various 1,2‐epoxides in water as a solvent, using no catalyst and under very mild conditions, is described.

Abstract

Synth. Commun. 2007, 37, 3245

PART 6: SYNTHESIS OF SPIRO 1,5‐BENZODIAZEPINE ATTACHED WITH DIFFERENT HETEROCYCLIC MOEITIES

A. Khodairy, A. M. El‐Sayed, H. Salah, and Abdel‐Ghany

Chemistry Department, Faculty of Science, Sohag, Egypt

3‐Oxime‐4‐phenyl‐1(H)(l,5)benzodiazepin‐2‐one 2,3‐bromo‐3‐cyano‐4‐phenyl‐l(H)(l,5)benzodiazepin‐2‐one 9a, 3‐bromo‐3‐cyano‐4‐(4′‐bromophenyl)‐1(H)(l,5)benzodiazepin‐2‐one 9b, 3‐(p‐tolylazo)‐4‐phenyl‐1(H)(1,5)‐benzodiazepin‐2‐one 17 were prepared and used as starting materials for the synthesis of spiro heterocyclic systems attached to the benzodiazepine moeity.