Synthesis of Some Novel 1,3,4‐Oxadiazol‐2‐yl‐4(3H)‐quinazolinones

Abstract

N‐1‐Aroyl‐2‐{[(3‐methyl‐4(3H)‐quinazolinone‐2‐yl)methyl]anilino} ethano hydrazides (4), prepared from 2‐phenylaminomethyl‐3‐methyl‐4(3H)‐quinazolinone (1), underwent PPA‐catalyzed cyclization the to title compounds 5 in 51–67% yield.

Keywords:

• ethylbromoacetate
• hydrazine hydrate
• 1,3,4‐oxadiazole
• polyphosphoric acid

Acknowledgment

Our sincere thanks to the director, IICT, Hyderabad, India, for providing spectral data and library facilities.