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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 41, 2010 - Issue 2
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Original Articles

Synthesis of 1,2,4,5-Tetrahydro-3,2-benzothiazepine 3,3-Dioxides Using Amberlyst-15

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Pages 200-205 | Received 19 May 2009, Published online: 15 Dec 2010
 

Abstract

A convenient method for the synthesis of 1,2,4,5-tetrahydro-3,2-benzothiazepine 3,3-dioxides from 2-phenylethanesulfonamides and formaldehyde using Amberlyst resin as catalyst is described.

ACKNOWLEDGMENTS

The authors thank UNLP and CICBA for financial support and Drs. Agustín Ponzinibbio and Ruben Rimada for NMR measurements.

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