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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 41, 2010 - Issue 2
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Original Articles

Stereoselective Bromination of 2-Vinyl Chromones Using NBS

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Pages 219-226 | Received 22 Aug 2009, Published online: 15 Dec 2010
 

Abstract

A simple one-step synthetic methodology for stereoselective synthesis of E- and Z-3-bromo-2-vinyl chromones in quantitative yield in polar solvents under ambient conditions without the use of catalysts is reported.

ACKNOWLEDGMENTS

S. B. gratefully acknowledges the financial assistance provided by the Department of Science and Technology for the study. The invaluable contributions by Dr. Shakti Sahi in carrying out energy calculations using Macromodel software are gratefully acknowledged. The assistance provided by the Indian Institute of Technology, New Delhi, and Central Drug Research Institute, Lucknow, for analytical analysis of the samples are gratefully acknowledged. All authors gratefully acknowledge infrastructure facilities provided by Amity Institute of Biotechnology, Amity University, Noida.

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