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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 41, 2011 - Issue 11
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Original Articles

Expedient Synthesis of cis- and trans-3-Aminocyclobutanecarboxylic Acids

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Pages 1644-1649 | Received 29 Oct 2009, Published online: 20 Apr 2011
 

Abstract

An expedient approach to cis- and trans-3-aminocyclobutanecarboxylic acids was developed starting from 1,1-cyclobutanedicarboxylic acid. Stereochemistry of the title compounds was established by nuclear Overhauser effect spectroscopy experiments.

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