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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 41, 2011 - Issue 15
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Original Articles

Use of Magnesium (Turnings) as a Powerful Catalyst for the O-Acylative Cleavage of Tetrahydrofuran

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Pages 2309-2314 | Received 19 Feb 2010, Published online: 25 May 2011
 

Abstract

In a short reaction time, acyl chlorides and dry tetrahydrofuran react in the presence of a catalytic amount of magnesium turnings (Mg) at 25 °C to give 4-chlorobutyl esters in excellent yields.

ACKNOWLEDGMENT

Krishnappa Manjula is thankful to V. P. Jayashankara for his timely help and encouragement.

Notes

a 0.024 g of Mg.

b Products are characterized by IR, 1H NMR, and LC–mass spectral analysis.

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