Oxidation of Alcohols to Aldehydes and Ketones Using TBHP as an Oxidant over LaMO₃ (M ˭ Cr, Mn, Co, Ni, Fe) Perovskites

Abstract

Oxidation of a wide variety of structurally and electronically diverse primary and secondary alcohols to aldehydes and ketones was carried out using a novel catalytic system of LaCrO₃ and tert-butyl hydroperoxide (TBHP) under solvent-free conditions. The methodology afforded the desired carbonyl compounds in good to excellent yields, and the catalyst can be reused several times with no significant loss in activity.

GRAPHICAL ABSTRACT

Keywords:

• Alcohol oxidation
• carbonyl compounds
• perovskite catalyst

ACKNOWLEDGMENT

S. J. S. thanks the Council of Scientific and Industrial Research, New Delhi, India, for the award of a senior research fellowship.

Notes

^a Reaction conditions: 1-phenyl ethanol = 1 mmol, 70% TBHP = 0.129 g (1 mmol equivalent of TBHP), oxide = 10 mol %, time = 0.5 h, temperature = 90 °C.

^b Yield determined by GC and GCMS analysis.

^a Reaction conditions: 1-phenyl ethanol = 1 mmol, 70% TBHP = 0.129 g (1 mmol equivalent of TBHP), time = 0.5 h, temperature = 90 °C.

^b Yield determined by GC and GCMS analysis.

^c Without TBHP.

^a Reaction conditions: alcohol = 10 mmol, 70% TBHP = 1.29 g (10 mmol equivalent of TBHP), LaCrO₃ = 1 mmol, temperature = 90 °C.

^b Isolated yields.

^a Reaction conditions: alcohol = 1 mmol, 70% TBHP = 0.129 g (1 mmol equivalent of TBHP), LaCrO₃ = 0.1 mmol, temperature = 90 °C.

^b Yields determined by GC and GCMS analysis.

^c In presence of 1 mmol radical scavenger.