Abstract
A greener and more efficient protocol for the synthesis of 12-aryl or 12-alkyl-8,9,10,12-tetrahydrobenzo[α]xanthen-11-one derivatives has been developed via one-pot, three-component reaction of aromatic aldehydes, 2-naphthol, and 1,3-cyclohexadione or 5,5-dimethyl 1,3-cyclohexadione using manganese perchlorate hydrate as a catalyst under ultrasonic irradiation. Good yield, shorter reaction time, simple workup procedure, and milder reaction conditions make this protocol efficient and environmentally benign.
GRAPHICAL ABSTRACT
ACKNOWLEDGMENT
The authors are grateful to the head of the Department of Chemistry, Sant Longowal Institute of Engineering and Technology, Longowal, for providing laboratory facilities.