Efficient One-Pot Synthesis of Tetrahydrobenzo[c]xanthene-1,11-dione Derivatives Under Microwave Irradiation

Abstract

An efficient one-pot condensation of 4-hydroxylcoumarin, aromatic aldehydes, and 5,5-dimethylcyclohexane-1,3-dione has been achieved with molecular iodine as a catalyst via conventional heating and microwave irradiation techniques, and thus a variety of new tetrahydrobenzo[c]xanthene-1,11-dione derivatives were prepared in good yields.

GRAPHICAL ABSTRACT

Keywords:

• 4-Hydroxylcoumarin
• microwave irradiation
• molecular iodine
• one-pot synthesis

ACKNOWLEDGMENT

We are grateful to the Jiangsu Key Laboratory of Chemistry of Low-Dimensional Materials.

Notes

^a Microwave power: 100 W, temperature: 120 °C.

^b Yields of the isolated products.