Abstract
Application of Fe3O4 nanoparticles (NPs) as a robust, very efficient, and magnetically recoverable catalyst was investigated in Friedel–Crafts acylation (FCA) of ferrocene and aromatic compounds. This reaction was performed with acid chlorides in solvent-free conditions at room temperature. The catalyst was easily separated by an external magnetic field from the reaction mixture. The separated catalyst was recycled for several consecutive runs without appreciable loss of its catalytic activity.
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ACKNOWLEDGMENTS
We thank the Yasouj University Research Council and the Iranian Nanotechnology Initiative Council for financial support.
Notes
a Isolated yield.
b Reported from Ref. 8c.
c Synthesized according to Ref. 10.
d 0.05 mmol Fe3O4 NPs.
e 0.1 mmol Fe3O4 NPs.
a The reaction was carried out on a 100-mmol scale.