Fermented Baker's Yeast: An Efficient Catalyst for the Synthesis of Pyran Derivatives in Water at Room Temperature

Abstract

An environmentally friendly, one-pot synthesis of biologically important pyran derivatives in water is described herein. The advantages of this method are its simplicity, cost-effectiveness, and environmental friendliness. Water was exploited both as reaction media as well as activator of catalyst (fermentation of bakers' yeast). Compared with other methods for synthesis of pyran derivatives, satisfactory results were obtained with good yields under simple experimental procedure.

GRAPHICAL ABSTRACT

Keywords:

• Bakers' yeast
• dimedone
• 4-hydroxy coumarin

ACKNOWLEDGMENTS

We thank to the University Grants Commission–Funding for Infrastructure in Science and Technology and Department of Science and Technology–SAP, Department of Chemistry, North Eastern Hill University.

Notes

^a The yields refer to isolated yields.

^a The yields refer to isolated yields.