New Synthesis of β-Anilinochalcones by Regioselective Oxidation of β-Anilinodihydrochalcones Using Iodine–DMSO

Abstract

β-Anilinodihydrochalcones readily undergo oxidation α to the carbonyl group region in the presence of a catalytic amount of iodine in dimethyl sulfoxide at 130 °C in good yield. Oxidation of allyloxy-substituted β-anilinodihydrochalcones to β-anilinochalcones is a preferred reaction over deallylation.

GRAPHICAL ABSTRACT

Keywords:

• β-Anilinochalcone
• dehydrogenation
• dimethyl sulfoxide
• iodine

Notes

^a Isolated yields of the product.

^b Products are characterized by spectral analysis.

^a Isolated yields of the product

^b Products are characterized by spectral analysis.