Selective and Efficient Deoxygenation of Sulfoxides with NbCl₅/Indium System

Abstract

It has been found that dialkyl, diaryl, and aryl alkyl sulfoxides can be selectively converted to the corresponding sulfides with a NbCl₅/In system in good to excellent yields under mild conditions. Several functional groups (bromo, chloro, methoxy, aldehyde, and vinyl) were tolerated under the reaction conditions.

Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications® to view the free supplemental file.

GRAPHICAL ABSTRACT

Keywords:

• Deoxygenation
• indium
• niobium
• sulfide
• sulfoxide

ACKNOWLEDGMENT

This work was financially supported by Korea University.

Notes

^a Refers to isolated yields.

^b The products were characterized by comparison of their spectroscopic and physical data with reported values.