Abstract
Heating a mixture of isatoic anhydride, amines, and N,N′-dialkyl carbodiimides under solvent-free conditions provided novel 3-alkyl-2-(alkylamino)quinazolin-4(3H)-one derivatives for the first time. The products were obtained in moderate to good yields without formation of any by-products.
Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications® to view the free supplemental file.
GRAPHICAL ABSTRACT
ACKNOWLEDGMENTS
This research was supported by grants from the research council of Tehran University of Medical Sciences and Iran National Science Foundation (INSF).
Notes
a Isolated yields.