Abstract
Based on x-ray diffraction analysis, we have proved that the recently published results for ethyl 6-amino-5-cyano-4-aryl-1,4-dihydropyridine-3-carboxylate synthesis is in fact an environmentally friendly synthesis of 6-amino-5-cyano-4-aryl-4H-pyran derivatives using a multicomponent room-temperature grinding procedure of ethyl acetoacetate, [(2-aryl)methylene]malononitriles, and ammonium acetate.
GRAPHICAL ABSTRACT
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ACKNOWLEDGMENT
This work was supported by ESF Project No. 2009/0197/1DP/1.1.1.2.0/09/APIA/VIAA/014.