Abstract
2,4,6-Tribromo-1,3,5-trihydroxybenzene (TBTHB) as a reagent was efficiently reacted with 6 molar equivalents of benzothioamides in dimethyl sulfoxide (DMSO), and the corresponding 3,5-diaryl-1,2,4-thiadiazoles were obtained in almost quantitative yields (91–98%) and in short times (15–20 min) with the formation of hexahydroxybenzene as a rather valuable by-product.
GRAPHICAL ABSTRACT
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ACKNOWLEDGMENT
The authors warmly acknowledge University of Isfahan Research Council for providing the facilities for this research.
SUPPLEMENTAL MATERIAL
Full experimental details and 1H and 13C NMR spectra for this article can be accessed on the publisher’s website.