Green Aspect for Multicomponent Synthesis of Spiro[4H-indeno[1,2-b]pyridine-4,3′-[3H]indoles]

Abstract

An efficient, four-component reaction of isatin, 1,3-indanedione, ethyl acetoacetate, and ammonium acetate in ethanol/water (9:1) system furnished spiro[4H-indeno[1,2-b]pyridine-4,3′-[3H]indoles] at room temperature. Merits of the method are mild reaction conditions, simple workup procedure, and ambient temperature. The synthesized compounds exhibit excellent fluorescence properties.

GRAPHICAL ABSTRACT

Keywords:

• Ambient temperature
• ammonium acetate
• 1,3-indanedione
• multicomponent
• spiro[4H-indeno[1,2-b]pyridine-4,3′-[3H]indoles]

ACKNOWLEDGMENTS

We are grateful to Prof. S. R. Patil and Mr. P. G. Mahajan, Department of Chemistry, Shivaji University, Kolhapur, for fluorescence study of synthesized compounds and fruitful discussion on it.

SUPPLEMENTAL MATERIAL

Supplemental data for this article can be accessed on the publisher’s website.

Additional information

Funding

D. M. P. is thankful to the University Grants Commission, New Delhi, for financial assistance [F. No. 42- 394/2013(SR)].