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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 46, 2016 - Issue 10
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Original Articles

Isolation and conversion of penicillic acid to 6-iodo-α-pyran-2,5-dione: A key intermediate for the synthesis of pectinolide F

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Pages 902-908 | Received 05 Jan 2016, Published online: 03 Jun 2016
 

ABSTRACT

Penicillic acid was isolated from Aspergillus sclerotiorum and converted into 6-iodo-α-pyran-2,5-diones using iodolactonization, a key intermediate for the synthesis of pectinolide F. Structures of penicillic acid and its iodolactonized product were confirmed by using NMR experiments.

GRAPHICAL ABSTRACT

Acknowledgments

Authors are thankful to the director of IIIM Jammu for the encouragement.

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