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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 46, 2016 - Issue 21
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Original Articles

Metal-free oxidation of secondary benzylic alcohols using aqueous TBHP

, , , , &
Pages 1747-1758 | Received 02 Apr 2016, Published online: 14 Oct 2016
 

ABSTRACT

We report a simple, yet efficient metal-free oxidation of secondary benzylic alcohols in the presence of t-butyl hydroperoxide (70% TBHP) with high yields of up to 98%. This type of reaction can be carried out using a wide variety of substrates, requires no other organic solvent, and proves to be tolerant toward a variety of different functional groups.

GRAPHICAL ABSTRACT

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