Facile synthesis of novel 3-substituted pyrido[1,2-a]pyrimidinium salts using vinamidinium salts

ABSTRACT

Pyrido[1,2-a]pyrimidinium salt derivatives 2a–f were prepared in good yields by condensation of 2-aminopyridine with 2-substituted vinamidinium salt derivatives 1a–f. The purity and the structure of the synthetized compounds were ascertained by elemental analysis, mass spectrometry, infrared, and NMR (¹H and ¹³C 400 MHz) spectroscopy.

GRAPHICAL ABSTRACT

KEYWORDS:

• 2-Amino pyridine
• 3-substituted pyrido[1,2-a]pyrimidinium salt derivatives
• Vilsmeier reaction
• vinamidinium salts

Acknowledgments

Financial support of this work by the Research Council of the Persian Gulf University is gratefully acknowledged.