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Abstract
Agastaquinone is a tricyclic diterpenoid isolated from Agastache rugose. The first total synthesis of agastaquinone was accomplished based on intramolecular Friedel-Crafts acylation of aryl lactone followed by aromatization leading to the tricyclic phenol core structure as a key step.
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Additional information
Funding
This work was supported from the R&D Convergence Program [CAP-16-03-KRIBB] of National Research Council of Science & Technology (NST) of Republic of Korea and KRIBB Research Initiative Program.