L-Cysteine capped Zn nanoparticles catalyzed synthesis of guanidines

Abstract

A highly chemoselective method for the coupling of carbodiimides with primary amines to synthesize guanidines is achieved using L-cysteine capped zinc nanoparticles (NPs) as a catalyst. The efficiency of the catalyst is proved by recyclability and reusability studies. Surface characterization of the catalyst before and after its repetitive usage proved the stability of the catalyst.

Graphical Abstract

Keywords:

• Carbodiimides
• coupling
• cysteine
• guanidines
• Zn nanoparticles

Additional information

Funding

Authors are grateful to Science and Engineering Research Board, India, for the financial assistance [Grant number: ECR/2016/001523].