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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 51, 2021 - Issue 5
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Articles

The synthesis of novel type of α-aminoketones containing allomaltol fragment

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Pages 701-708 | Received 25 Aug 2020, Published online: 24 Nov 2020
 

Abstract

A novel efficient one-step method for the preparation of α-aminoketones was developed based on multicomponent reaction of allomaltol, arylglyoxals and primary amines. The advantages of this synthesis are good yields, mild reaction conditions, atom economy and easy workup procedure without chromatographic purifications.

Graphical Abstract

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