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Abstract
Synthesis of 1,3,4-oxadiazoles by employing carbimidothioates and benzohydrazides in presence of p-toluenesulfonic acid in dioxane solvent at reflux condition is reported. The presented procedure is noteworthy for its quick reaction time, high yield, broad application and less hazardous. The probable mechanism of production of 1,3,4-oxadiazoles is presented.
Graphical abstract
Acknowledgments
The authors gratefully credit the UPE, CPEPA and DST Purse programmes, as well as Vijnana Bhavana, University of Mysore, Mysuru for supplying the essential instrumentation facilities.
Disclosure statement
No potential conflict of interest was reported by the author(s).
Additional information
Funding
This research was supported by the University of Mysore and funded by the SERB-DST Ramanujan Fellowship in New Delhi.