https://orcid.org/0000-0002-7535-1310
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Abstract
An effective, green and eco-friendly method was developed to synthesize 1H-benzimidazole under microwave irradiation. The reactions of substituted o-phenylenediamine with DMF were efficiently promoted by butanoic acid, and the desired product 1H-benzimidazole derivatives were obtained in good to excellent yields. Compared with the conventional heating method, microwave irradiation significantly reduced the reaction time and improved the yields of the target products.
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Disclosure statement
The authors declare no conflict of interest.
Additional information
Funding
This work was supported by the Program for Grassland Excellent Talents of Inner Mongolia Autonomous Region, the National Natural Science Foundation of China (21865020), the Natural Science Foundation of Inner Mongolia (No.2021ZD02), Inner Mongolia Science and Technology Key Projects (2021GG0335) and Innovative Research Team in Universities of Inner Mongolia Autonomous Region (NMGIRT2212) and the Program for Young Talents of Science and Technology in Universities of Inner Mongolia Autonomous Region (2019).