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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 9, 1979 - Issue 5
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Original Articles

Pyridylethylation and Quinolylethylation of Isopropylidene Malonates

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Pages 383-389 | Received 13 Nov 1978, Published online: 06 Dec 2006
 

Abstract

The Michael-type addition of carbanionic reagents to 2- and 4-vinylpyridines has been widely examined and utilized in organic synthesis.1 When malonic esters are employed, the usual procedure is to reflux the reagents in ethanol containing sodium ethoxide. However, the yields of these reactions have been somewhat variable2.

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