Facile Synthesis of γ-Butyrolactones

R. Verhé Laboratory of Organic Chemistry Faculty of Agricultural Sciences State, University of Gent, Coupure 533, B-9000, GENT, Belgium

N. De Kimpe Laboratory of Organic Chemistry Faculty of Agricultural Sciences State, University of Gent, Coupure 533, B-9000, GENT, Belgium

L. De Buyck Laboratory of Organic Chemistry Faculty of Agricultural Sciences State, University of Gent, Coupure 533, B-9000, GENT, Belgium

N. Schamp Laboratory of Organic Chemistry Faculty of Agricultural Sciences State, University of Gent, Coupure 533, B-9000, GENT, Belgium

Abstract

During the course of our investigations concerning the synthesis of allylic bromides bearing two electron-Withdrawing groups, it has been observed that Knoevenagel condensation products derived from aliphatic aldehydes and active methylene functions showed a tendency to undergo ring closure.¹

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Facile Synthesis of γ-Butyrolactones

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Facile Synthesis of γ-Butyrolactones

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