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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 16, 1986 - Issue 14
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Original Articles

2-Formyl-3-Methoxymethylindole, 3-Ethoxymethyl-2-Formylindole and 2-Formyl-3-Methylindole

David W.M. Benzies School of Chemical Sciences, University of East Anglia, Norwich, NR4 7TJ, England
,
Pilar Martinez Fresneda School of Chemical Sciences, University of East Anglia, Norwich, NR4 7TJ, England
&
R. Alan Jones School of Chemical Sciences, University of East Anglia, Norwich, NR4 7TJ, England
Pages 1799-1807 | Published online: 05 Dec 2006
 
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Abstract

Base-catalysed hydrolysis of 2-formyl-3-methyl-1-phenyl-sulphonylindole results in the formation of 3-alkoxy-methyl-2-formylindoles. Cleavage of the 1-phenyl-sulphonyl group with sodium amalgam produces 2-hydroxymethyl-3-methylindole.

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